Coffee

From

Summary

TBD.

Studies and Reports

• Wynder E et al., [http://www.ncbi.nlm.nih.gov/pubmed/3756885 Case-control study of decaffeinated coffee consumption and pancreatic cancer Cancer Res. 46(10):5360-3, October 1986.
  • Abstract. "The relationship between decaffeinated coffee consumption and pancreatic cancer was examined using data from a hospital-based case-control study of individuals aged 20-80 years in 18 hospitals in 6 United States cities, from January 1981 to December 1984. Among the males, 127 cases and 371 controls were examined, while for females, the figures were 111 and 325 for cases and controls, respectively. Decaffeinated coffee use was not associated with an increased risk of pancreatic cancer in males (odds ratio = 0.7 for 3 or more cups/day; 95% confidence interval = 0.4-1.4). For females, an elevated risk was seen for drinkers of 1-2 cups/day (odds ratio = 1.6; 95% confidence interval = 1.0-2.7), but this finding was of borderline significance and elevation in risk was not found for drinkers of 3 or more cups/day (odds ratio = 0.9; 95% confidence interval = 0.4-1.9). Cigarette smoking was significantly associated with pancreatic cancer in both males and females. Factors examined and not found to be related to pancreatic cancer included education, occupation, religion, marital status, alcohol drinking, saccharin use, height, weight 5 years before hospitalization, history of previous diseases, and residence."
• Wynder et al., Epidemiology of coffee and pancreatic cancer, Cancer Res. 43(8):3900-6, August 1983.
  • Abstract. "The association between pancreatic cancer and putative risk factors was examined using 275 incident cases and 7994 controls interviewed in six United States cities for a major study of tobacco-related diseases. From the comparison population were excluded patients with other diseases postulated to be associated with pancreatic cancer (e.g., other pancreatic diseases and diseases of the gallbladder) and those admitted for disorders known to be associated with smoking. After carefully controlling for age, the data failed to indicate an association between coffee consumption and pancreatic cancer (odds ratio congruent to 1.0). This was true both before and after adjustment for cigarette smoking and in both males and females. There was a statistically significant association between pancreatic cancer and smoking in both males and females (odds ratio 3.0 for males who smoked more than 1.5 packs/day and 2.0 for females who smoked more than 1 pack/day)."

Additional Resources

• Whelan E, Coffee Causes Cancer! Oops, This Just In! Coffee Prevents Cancer!, TechCentralStation, February 28, 2005.
• Facts Versus Fears (Fourth Edition) A Review of the Greatest Unfounded Health Scares of Recent Times, American Council on Science and Health, September 28, 2004.